Select the most appropriate ANTONYM of the underlined word in the given sentence.

God has clearly blessed human beings for his glory.

The correct answer is option 4), i.e., 'cursed.'

Key Points 

• Let's look at the meanings of the given word and marked option:

  Word	Meaning
  blessed	holy; bringing you happiness, luck, or something you need. (पवित्र; आपके लिए खुशी, भाग्य, या आपकी जरूरत की कोई चीज लाना)
  cursed	experiencing bad luck caused by a magic curse; experiencing problems and unhappiness. (एक जादू अभिशाप के कारण दुर्भाग्य का अनुभव करना; समस्याओं और दुख का अनुभव करना)

• ​Let's look at the meanings of the other given options:

  Word	Meaning
  Appointed	officially chosen for a job or responsibility. (आधिकारिक तौर पर नौकरी या जिम्मेदारी के लिए चुना गया)
  Produced	to make something or bring something into existence. (कुछ बनाने या कुछ अस्तित्व में लाने के लिए)
  Applied	relating to a subject of study, especially a science, that has a practical use. (अध्ययन के एक विषय से संबंधित, विशेष रूप से एक विज्ञान, जिसका व्यावहारिक उपयोग है)

• Hence from the given meanings, we find that 'blessed' and 'cursed' are antonyms.
• So, the correct answer is option 4.