Match List-I with List-II.

List-I	List-II
A. Alfred Hershey and Martha Chase	I. Streptococcus Pneumoniae
B. Euchromatin	II. Densely packed and dark-stained
C. Frederick Griffith	III. Loosely packed and light-stained
D. Heterochromatin	IV. DNA as genetic material confirmation

Choose the correct answer from the options given below:

The correct answer is A-IV, B-III, C-I, D-II

Explanation:

• A. Alfred Hershey and Martha Chase - IV. DNA as genetic material confirmation: Hershey and Chase conducted the famous "blender experiment" which confirmed that DNA, and not protein, is the genetic material in bacteriophages. 
  • The unequivocal proof that DNA is the genetic material came from the experiments of Alfred Hershey and Martha Chase (1952).
  • They worked with viruses that infect bacteria called bacteriophages. 
  • The experiment used the T2 bacteriophage, a type of virus that infects bacteria. The bacteriophage consists of a protein coat and DNA.
• B. Euchromatin - III. Loosely packed and light-stained: Euchromatin is a form of chromatin that is loosely packed and appears light under a microscope, allowing active gene transcription.
• C. Frederick Griffith - I. Streptococcus Pneumoniae: Griffith's experiments involved Streptococcus pneumoniae bacteria, leading to the discovery of the phenomenon of transformation.
  • The "Transforming Principle" is a term used to describe the substance responsible for transformation in bacteria, which was first identified by Frederick Griffith in 1928.
  • Griffith's experiments involved two strains of the bacterium Streptococcus pneumoniae, a virulent smooth strain (S) and a non-virulent rough strain (R).
• D. Heterochromatin - II. Densely packed and dark-stained: Heterochromatin is tightly packed chromatin that appears dark under a microscope and is generally transcriptionally inactive.