Question
Download Solution PDFNegatively charged DNA is wrapped around histone octamer to form:
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AIIMS BSc NURSING 2023 Memory-Based Paper
Answer (Detailed Solution Below)
Option 2 : Nucleosome
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AIIMS BSc NURSING 2024 Memory-Based Paper
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Detailed Solution
Download Solution PDFThe correct answer is Nucleosome
Explanation:
- The nucleosome, a section of DNA wrapped around a core of proteins, is the fundamental subunit of chromatin.
- Each nucleosome is comprised of a little less than two turns of DNA wrapped around a set of eight proteins called histones, which are known as a histone octamer.
- The negatively charged DNA is wrapped around the positively charged histone octamer (protein) to form a structure called a nucleosome.
- Each nucleosome is comprised of a little less than two turns of DNA wrapped around a set of eight proteins called histones, which are known as histone octamer.
- Each histone octamer is composed of two copies of each of the histone proteins H2A, H2B, H3, and H4.
- A typical nucleosome contains 200 bp of DNA helix.
- Nucleosomes constitute the repeating unit of a structure in the nucleus called chromatin, threadlike stained (coloured) bodies seen in the nucleus.
- The nucleosomes in chromatin are seen as ‘beads-on-string’ structures when viewed under an electron microscope (EM).
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