Why Is DNA Negatively Charged? - Structure & Functions of DNA

Last Updated on Dec 12, 2023
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The negative charge of DNA is attributed to the phosphate groups that are part of its nucleotides.

The DNA's phosphate backbone carries a negative charge due to the bonds formed between phosphorus and oxygen atoms.

Within the structure of DNA, one negatively charged oxygen atom is part of the phosphate group, giving the entire DNA strand its negative charge.

Let's delve deeper into the fascinating world of DNA and its structure.

Defining DNA

DNA or Deoxyribonucleic Acid is a hereditary material present in all living entities, from simple unicellular organisms to complex multicellular organisms like plants, animals, birds, mammals, and humans.

DNA, an organic compound with a unique molecular structure, can be found in both prokaryotic and eukaryotic cells. This hereditary material is composed of nucleotide molecules.

Swiss Biologist, Johannes Friedrich Miescher, first discovered DNA in 1869 while studying white blood cells.

The double-helix structure of a DNA molecule was later discovered by James Watson and Francis Crick. They also established that DNA molecules play a crucial role in storing and transmitting genetic information in all living organisms.

The Structure of DNA

DNA, the basic genetic blueprint of all life on earth, is a molecule made up of nitrogenous bases, sugar molecules, and phosphate groups.

DNA's structure is a double helix, resembling a twisted ladder. It consists of two strands, each with a backbone made of alternating sugar (deoxyribose) and phosphate groups.

DNA is made up of nucleotides, each containing:

  1. A phosphate group
  2. A sugar group
  3. One of four different types of nitrogen bases – Adenine (A), Thymine (T), Guanine (G), and Cytosine (C).

Varieties of DNA

DNA can exist in three different forms:

  1. A-DNA — Right-handed helix
  2. B-DNA — Right-handed helix
  3. Z-DNA — Left-handed helix

In humans, we predominantly find B-DNA, a right-handed double-helical structure.

The Role of DNA

DNA plays critical roles in:

  1. Mutation
  2. Translation
  3. Replication
  4. Transcription
  5. Gene expression

For more information: DNA Structure

For a deeper understanding of DNA, its importance, the reason for its negative charge, and more, explore Biology

 
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Frequently Asked Questions

DNA is negatively charged because of the presence of phosphate groups in its nucleotides. The phosphate backbone of DNA has a negative charge due to the bonds created between the phosphorus and oxygen atoms.

DNA, or Deoxyribonucleic Acid, is an inherited material found in every living species. It has a unique molecular structure and is found in both prokaryotic and eukaryotic cells.

The structure of DNA is a double helix. It comprises two strands that are coiled or wrapped around each other. Each strand has a backbone made of alternating sugar (deoxyribose) and phosphate groups.

There are three different types of DNA: A-DNA, B-DNA, and Z-DNA.

DNA is involved in mutation, translation, replication, transcription, and gene expression.

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