What is the main function of the spindle fibers during mitosis? 

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NEET 2025 Official Paper (Held On: 04 May, 2025)
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  1. To separate the chromosomes  
  2. To synthesize new DNA
  3. To repair damaged DNA 
  4. To regulate cell growth 

Answer (Detailed Solution Below)

Option 1 : To separate the chromosomes  
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CT 1: Botany (Cell:The Unit of Life)
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The correct answer is To separate the chromosomes

Explanation:

  • Mitosis is the process of cell division in eukaryotic cells that results in two genetically identical daughter cells. This process is crucial for growth, repair, and asexual reproduction in multicellular organisms.
  • Spindle fibers are protein structures formed during cell division. They originate from the centrosomes (or spindle pole bodies in some organisms) and play a critical role in ensuring the chromosomes are properly aligned and separated.
  • The spindle fibers attach to the centromeres of the chromosomes through structures called kinetochores. This attachment is essential for the correct segregation of chromosomes during mitosis.
  • During metaphase, spindle fibers align the chromosomes along the metaphase plate (the center of the cell). This ensures that each daughter cell will receive an identical set of chromosomes.
  • In anaphase, spindle fibers pull the sister chromatids apart by shortening, ensuring that one copy of each chromosome moves to opposite poles of the cell. This separation is important for maintaining the correct chromosome number in daughter cells.
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