Which one of the following statements best describes the role of B cells and T cells in the human body?

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UPSC Civil Services Exam Official 2022 Prelims General Studies held on 5th June
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  1. They protect the body from environmental allergens.
  2. They alleviate the body's pain and inflammation.
  3. They act as immunosuppressants in the body.
  4. They protect the body from the diseases caused by pathogens.

Answer (Detailed Solution Below)

Option 4 : They protect the body from the diseases caused by pathogens.
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The correct answer is option 4.

Key PointsB cells and T cells:

  • B cells and T cells are the main types of lymphocytes. 
    • B cells work chiefly by secreting substances called antibodies into the body’s fluids. Antibodies ambush antigens circulating the bloodstream. 
    • They are powerless, however, to penetrate cells. The job of attacking target cells—either cells that have been infected by viruses or cells that have been distorted by cancer—is left to T cells or other immune cells.
    • Each B cell is programmed to make one specific antibody. For example, one B cell will make an antibody that blocks a virus that causes the common cold, while another produces an antibody that attacks a bacterium that causes pneumonia. They protect the body from the diseases caused by pathogens. Hence, Statement 4 is correct.
    • When a B cell encounters its triggering antigen, it gives rise to many large cells known as plasma cells. 
    • Every plasma cell is essentially a factory for producing an antibody. 
    • Each of the plasma cells descended from a given B cell manufactures millions of identical antibody molecules and pours them into the bloodstream. 
    • An antigen matches an antibody much as a key matches a lock. Some match exactly; others fit more like a skeleton key. 
    • But whenever antigen and antibody interlock, the antibody marks the antigen for destruction.
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