Which of the following deficiency of vitamin causes Beriberi?

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JKSSB SI Official Paper (Held On: 08 Dec 2022 Shift 1)
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  1. C
  2. B5
  3. B1
  4. B12

Answer (Detailed Solution Below)

Option 3 : B1
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The correct answer is Vitamin B1.

Key Points

  • Beriberi is caused by a deficiency of Vitamin B1, also known as thiamine.
  • Thiamine is crucial for the body's ability to convert food into energy, particularly in the metabolism of carbohydrates.
  • There are two main types of beriberi: wet beriberi (affecting the cardiovascular system) and dry beriberi (affecting the nervous system).
  • Symptoms of beriberi can include weight loss, emotional disturbances, impaired sensory perception, weakness and pain in the limbs, and periods of irregular heart rate.

Additional Information

  • Thiamine (Vitamin B1)
    • Thiamine is a water-soluble vitamin that plays a key role in glucose metabolism and is essential for the functioning of the nervous system, muscles, and heart.
    • Good dietary sources of thiamine include whole grains, meat (especially pork), and fish.
    • Thiamine deficiency can result from poor dietary intake, chronic alcoholism, or certain medical conditions that affect absorption.
    • Recommended daily intake of thiamine varies by age, sex, and physiological status, with higher needs during pregnancy and lactation.
  • Symptoms of Thiamine Deficiency
    • Early symptoms can include fatigue, irritability, poor memory, sleep disturbances, and gastrointestinal issues.
    • Severe deficiency can lead to beriberi or Wernicke-Korsakoff syndrome, which is associated with neurological symptoms.
    • Treatment involves thiamine supplementation and dietary modifications to ensure adequate intake.
  • Wernicke-Korsakoff Syndrome
    • A severe neurological disorder caused by thiamine deficiency, often associated with chronic alcoholism.
    • Characterized by symptoms such as confusion, coordination problems, eye abnormalities, and memory impairment.
    • Requires immediate medical treatment with thiamine supplementation to prevent permanent damage.
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