Amoebiasis is a disease in which the pathogen affects the - 

The correct answer is Intestine.

Key Points

• Amoebiasis is caused by the parasite Entamoeba histolytica, which primarily affects the human intestine.
• The disease spreads through contaminated food and water, making it a major concern in areas with poor sanitation.
• Symptoms of intestinal amoebiasis include diarrhea, abdominal pain, and blood-stained stool.
• The parasite invades the intestinal lining, leading to ulcers and tissue damage.
• If untreated, amoebiasis can progress to severe complications such as intestinal perforation or liver abscesses.

Additional Information

• Entamoeba histolytica:
  • A single-celled parasitic protozoan responsible for amoebiasis.
  • It has two forms: the infective cyst stage and the invasive trophozoite stage.
• Transmission:
  • Occurs through the ingestion of water or food contaminated with cysts of Entamoeba histolytica.
  • Direct person-to-person transmission is also possible in unsanitary conditions.
• Diagnosis:
  • Stool microscopy is used to detect the presence of trophozoites or cysts.
  • Serological tests and imaging techniques like ultrasound or CT scan are used to identify extra-intestinal complications like liver abscesses.
• Prevention:
  • Ensure access to clean drinking water and proper sanitation.
  • Practice good hygiene, such as regular handwashing before meals.
• Treatment:
  • Metronidazole or tinidazole is commonly prescribed to eliminate the infection.
  • Follow-up therapy with luminal agents like paromomycin is recommended to eradicate cysts from the intestine.