Sentinel lymph nodes serve as the primary drainage points for cancer cells. Cancer typically spreads in an orderly manner, starting with the lymph nodes due to the lymph's directional flow. A biopsy of sentinel nodes is critical for determining the extent of cancer spread. If the biopsy is negative, it is highly probable that the cancer cells haven't reached the lymph nodes. However, if the result is positive, it indicates the cancer-affected lymph area that needs surgical removal.
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Axillary lymph nodes are located in the human armpit and are responsible for draining lymph from the chest wall, breast, upper abdomen, and upper limb. These nodes are crucial in detecting the presence of breast cancer. Finding cancer cells in these nodes increases the risk of metastatic breast cancer.
Sentinel Lymph Nodes |
Axillary Lymph Nodes |
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They are the first lymph nodes to drain cancer cells. |
They are lymph nodes located in the human armpit. |
A biopsy of these nodes serves as the initial evaluation for cancer presence. |
A biopsy of these nodes can cause tissue disruption and is usually avoided until after a sentinel node biopsy. |
Biopsies of sentinel nodes do not lead to lymphedema. |
Biopsies of axillary nodes can result in lymphedema. |
Learn More: The Differences between Blood and Lymph
Further Reading: An Overview of the Composition and Function of Lymph in Humans
Explore more interesting topics at Biology Section
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