Which of the following is a sex-linked disease ?

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WBSSC SLST (Class 9-10) Life Science Official Paper Held On 04 Dec, 2016
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  1. Myopia
  2. Smallpox
  3. Scurvy
  4. Colour blindness.

Answer (Detailed Solution Below)

Option 4 : Colour blindness.
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The correct answer is Colour blindness.

Explanation:

  • Sex-linked diseases are genetic disorders that are associated with the sex chromosomes, primarily the X chromosome. These disorders are often passed down from parents to offspring.
  • Colour blindness is a common example of an X-linked recessive disorder. It is caused by mutations in the genes responsible for the production of photopigments in the eye.
  • It is due to defect in either red or green cone of eye resulting in failure to discriminate between red and green colour.
  • This defect is due to mutation in certain genes present in the X chromosome.
  • It occurs in about 8 per cent of males and only about 0.4 per cent of females.
  • Since males have only one X chromosome (XY), they are more likely to exhibit X-linked disorders.
  • Females (XX), on the other hand, need mutations in both X chromosomes to express the condition, making them less likely to be affected.

Other Options:

  • Myopia: Myopia, or nearsightedness, is a refractive error of the eye that causes difficulty in seeing distant objects clearly. 
  • Smallpox: Smallpox is a viral infection caused by the variola virus. It has been eradicated globally through vaccination programs
  • Scurvy: Scurvy is a nutritional deficiency disease caused by a lack of vitamin C (ascorbic acid) in the diet. 
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