Ortho-sulphobenzimide is also known as?

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  1. alitame
  2. saccharin 
  3. aspartame 
  4. sucralose

Answer (Detailed Solution Below)

Option 2 : saccharin 
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Detailed Solution

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The correct answer is Saccharin.

Key Points

  • Ortho-sulphobenzimide is the chemical name for saccharin, a widely used artificial sweetener.
  • Saccharin is approximately 300–400 times sweeter than sucrose (table sugar), making it a popular choice for low-calorie and sugar-free products.
  • It is non-nutritive, meaning it does not provide calories or energy when consumed, as it is not metabolized by the body.
  • Saccharin was discovered in 1879 by Constantin Fahlberg, a chemist working on coal tar derivatives at Johns Hopkins University.
  • It has been approved for use as a food additive by regulatory agencies like the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).

Additional Information

  • Artificial Sweeteners:
    • Artificial sweeteners are synthetic sugar substitutes that provide sweetness without the caloric content of sugar.
    • Common artificial sweeteners include aspartame, sucralose, alitame, and saccharin.
    • These are used in a variety of products such as soft drinks, chewing gum, baked goods, and toothpaste.
  • Health Impact of Saccharin:
    • Saccharin was controversially linked to cancer in the 1970s based on studies in rats, but subsequent research cleared it of posing significant risks to humans.
    • The World Health Organization (WHO) and other global health authorities consider it safe for human consumption within prescribed limits.
  • Acceptable Daily Intake (ADI):
    • The ADI for saccharin is 5 milligrams per kilogram of body weight, as established by regulatory bodies like the FDA and EFSA.
    • This ensures safe consumption levels for the general population.
  • Comparison with Other Sweeteners:
    • Saccharin is stable under heat and acidic conditions, unlike aspartame, which breaks down at high temperatures.
    • Sucralose is sweeter than saccharin (about 600 times sweeter than sugar) and is also heat-stable, making it suitable for cooking and baking.
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