Among the following, where does growth hormone produce in?

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JKSSB SI Official Paper (Held On: 16 Dec 2022 Shift 1)
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  1. Bone
  2. Pituitary gland
  3. Thyroid gland
  4. Adrenal gland

Answer (Detailed Solution Below)

Option 2 : Pituitary gland
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The correct answer is Pituitary gland.

Key Points

  • The growth hormone, also known as somatotropin, is produced in the anterior pituitary gland, which is located at the base of the brain.
  • This hormone plays a crucial role in stimulating growth, cell reproduction, and cell regeneration in humans and animals.
  • The secretion of growth hormone is regulated by the hypothalamus through releasing and inhibiting hormones (GHRH and somatostatin).
  • Growth hormone levels peak during puberty and are essential for proper development of bones and muscles.
  • Disorders in growth hormone production can lead to conditions like gigantism, acromegaly, or growth hormone deficiency.

Additional Information

  • Pituitary Gland:
    • Known as the "master gland," it controls several other hormone glands such as the adrenal gland and thyroid gland.
    • It consists of two parts: the anterior pituitary (produces growth hormone, ACTH, TSH, etc.) and the posterior pituitary (stores and releases oxytocin and vasopressin).
  • Growth Hormone-Releasing Hormone (GHRH):
    • A hormone produced by the hypothalamus that stimulates the anterior pituitary to release growth hormone.
    • Its secretion is influenced by factors like sleep, stress, and exercise.
  • Somatostatin:
    • Also known as growth hormone-inhibiting hormone (GHIH), it suppresses the release of growth hormone.
    • It is produced by the hypothalamus as well as other tissues like the pancreas.
  • Conditions Related to Growth Hormone:
    • Gigantism: Excess production of growth hormone during childhood, leading to abnormal height.
    • Acromegaly: Excess growth hormone in adulthood, causing thickening of bones and tissues.
    • Growth Hormone Deficiency: Inadequate production of growth hormone, leading to stunted growth in children.
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